The base price of $110,850 is up by more than $15,000, although 4Matic all-wheel drive is now standard across the board.

While it was previously possible to get a new Mercedes-Benz S-class for less than six figures, the new 2021 version of the full-size luxury sedan will start well above $100,000. The 2021 Mercedes S500 4Matic has a base price of $110,850, an increase of $15,650 over the 2020 model’s base price, while the new V-8–powered S580 4Matic starts at $117,350, an increase of $8905 over the previous S560 4Matic.
…
Continue here:
https://www.caranddriver.com/news/a35001935/2021-mercedes-benz-s-class-pricing/