The Canon EOS R and Panasonic Lumix S1 both represent their company’s first attempts at full-frame mirrorless cameras, and each manufacturer brings different competencies to the table. Canon has made many full-frame DSLRs before, while the S1 was Panasonic’s first full-frame camera, period. Panasonic has had much more experience building mirrorless cameras, however, having essentially founded the modern mirrorless era in 2008 with the Lumix G1.
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https://www.digitaltrends.com/photography/panasonic-lumix-s1-vs-canon-eos-r/
