One of the things that we’re almost certain of with any new Galaxy S model is that it will use a Snapdragon chipset in some parts of the world and an Exynos one in others, but with the Samsung Galaxy S22 range that might not be the case.

According to Super Roader (a South Korean leaker and ex Samsung employee) the Samsung Galaxy S22 range will use the Snapdragon 898 in all regions.

That won’t be a change for the US, but it would be for much of the rest of the world, including the UK, which typically gets Exynos models of Samsung’s flagships.
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