Below are crops from our laboratory Still Life target comparing the Fuji GFX 50R’s JPEG image quality to its bigger brother’s, the 50S. We’ve also compared it to other high-resolution cameras: the 50-megapixel full-frame Canon 5DS R, the 46-megapixel full-frame Nikon D850, the 51-megapixel medium format Pentax 645Z, and the 42-megapixel full-frame Sony A7R II Mark III.
NOTE: These images are from best quality JPEGs straight out of the camera, at default settings including noise reduction and using the camera’s actual base ISO (not extended ISO settings).
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https://www.imaging-resource.com/PRODS/fuji-gfx-50r/fuji-gfx-50r-image-quality.htm